Dr. Subha Rastogi

Principal Scientist

Research Interests

– Bioassay guided isolation of plant secondary metabolites

– Chromatographic fingerprinting and marker based standardization of medicinal plants and herbal formulations

– Development of analytical methods for qualitative and quantitative estimation of chemical biomarkers in medicinal plants. 

– Developing quality control parameters and pharmacopoeial standards for single herbal drugs and compound herbal formulations used in the Indian systems of medicine

 

Dr. Subha Rastogi

Principal Scientist

Research Summary

Dr. Subha Rastogi

Principal Scientist

Publications

– Subha Rastogi Raghwendra Pal and Dinesh K. Kulshreshtha. Bacogenin A5: A rearranged sapogenin from the saponins of Bacopa monniera. Indian Journal of Heterocyclic Chemistry. 1993, 2: 149-150.

 Subha Rastogi, Raghwendra Pal and Dinesh K.Kulshreshtha. Bacoside A3: A triterpenoid saponin from Bacopa monniera. Phytochemistry. 1994, 36(1): 133-137.

 Subha Rastogi and Dinesh K.Kulshreshtha. Bacoside A2: A triterpeniod saponin from Bacopa monniera. Indian Journal of Chemistry 1999, 38-B: 353-356.

 R.Govindarajan,, Subha Rastogi, M. Vijayakumar, A.K.S. Rawat, A. Shirwaikar, S. Mehrotra, P. Pushpangadan. Studies on the antioxidant activities of Desmodium gangeticum. Biological and Pharmaceutical Bulletin, 2003, 26(10): 1424-1427.

 P. Sharma, Subha Rastogi, S. Bhatnagar, JK Srivastava, A. Dubey, P. Y. Guru, D.K. Kulshreshtha, B.N. Mehrotra and BN. Dhawan. Antileishmanial action of Tephrosia purpurea Linn, extract and its fractions against experimental visceral leishmaniasis. Drug Development Research, 2003, 60: 285-293.

 Subha Rastogi, B.N. Mehrotra and D.K. Kulshreshtha. Constituents of Mallotus nepalensis Muell. Arg.: a mild CNS depressant. Natural Product Sciences, 2004, 10(5): 237-239.   

Subha Rastogi, S. Bala, R. Govindarajan, M. Shukla, A.K.S. Rawat and S. Mehrotra. Quantitative HPLC analysis of amino acids in Chyavanprash: A well known Ayurvedic formulation. Indian Journal of Pharmaceutical Sciences, 2004, 66(6): 753-757.

 Subha Rastogi, S. Khatoon, V. Rai, A.K. Agnihotri, A.K.S. Rawat and S. Mehrotra. Evaluation of Ayurvedic compound formulations 1- Naraca Curna.Indian Journal of Traditional Knowledge, 2005, 4(2): 185-189.

 Subha Rastogi, M.M. Pandey and A.K.S. Rawat. Determination of Heraclenin and Heraclenol in Heracleum candicans D.C. by TLC. Chromatographia 2007, 66: 631-634.

“A New, Convenient Method for Determination of Mangiferin, an Anti-Diabetic Compound, in Mangifera indica L.” Subha Rastogi, M.M. Pandey and A.K.S. Rawat. Journal of Planar Chromatography, 2007, 20(5): 317–320.

“Antifilarial activity of Caesalpinea bonducella against experimental filarial infections.” R.L. Gaur, M.K. Sahoo, S. Dixit, N. Fatma, Subha Rastogi, D.K. Kulshreshtha, R.K. Chatterjee and P.K. Murthy. Indian Journal of Medical Research, 2008, 128: 65-70.

“High-Performance Thin-Layer Chromatography Densitomertic Method for the Simultaneous Determination of Three Phenolic Acids in Sygyzium aromaticum (L.) Merr. & Perry.” Subha Rastogi, M.M. Pandey and A.K.S. Rawat. Journal of AOAC International, 2008, 91(5): 1169-1173.

“Optimization of a HPTLC method for the separation and identification of phenolics.” M.M. Pandey, Subha Rastogi and A.K.S. Rawat. Journal of Planar Chromatography, 2010, 23(2): 108-111.

In vitro and in vivo efficacy of Acorus calamus extract against Rhipicephalus (Boophilus) microplus.” S. Ghosh,  A.K. Sharma, S. Kumar, S.S. Tiwari, Subha Rastogi, S. Srivastava, M. Singh, R. Kumar, S. Paul, D.D. Ray and A.K.S. Rawat. Parasitology Research, 2011, 108: 361–370.

“Standardization of Ashwagandhadi lehya — an Important Ayurvedic Formulation of Withania somnifera.” Mansi Gupta, Deepa Bisht, M.M. Pandey, S.K. Ojha, S. Khatoon, Subha Rastogi and A.K.S. Rawat. Indian Journal of Traditional Knowledge, 2011, 10(4): 594-598.

“Phenolic content and antioxidant properties of some common Indian spices of Apiaceae.” M.M. Pandey, M. Vijayakumar, Subha Rastogi, and A.K.S. Rawat. Journal of Herbs, Spices and Medicinal Plants, 2012, 18(3): 246-256.

“Evaluation of Ayurvedic compound formulations 4- MusliCurna.” Subha Rastogi, S. Khatoon, M.M. Pandey, A.K.S. Rawat and S. Mehrotra. Indian Journal of Traditional Knowledge, 2012, 11(4): 680-684.

“Immunomodulatory and antioxidative potential of herb (Pueraria tuberosa) in mice using milk as the carrier.” Sawale Pravin Digambar, Ram Ran Bijoy Singh, Suman Kapila, Sumit Arora, Subha Rastogi and Ajay Kumar Singh Rawat. International Journal of Dairy Technology, 2013, 66: 202–206.

“An Important Indian Traditional Drug of Ayurveda Jatamansi and Its Substitute Bhootkeshi: Chemical Profiling and Antioxidant Activity.” M.M. Pandey, A. Katara, G. Pandey, Subha Rastogi and A.K.S. Rawat. Evidence-Based Complementary and Alternative Medicine, 2013, 142517, doi:10.1155/2013/142517

“Physical stability and HPLC analysis of Indian Kudzu (Pueraria tuberosa Linn.) fortified milk.” Subha Rastogi, A. Katara, M.M. Pandey, Sumit Arora, RRB Singh and A.K.S. Rawat. Evidence-Based Complementary and Alternative Medicine 2013, 368248, doi: 10.1155/2013/368248. 

 N. Veena, Sumit Arora, R.R.B. Singh, Antariksh Katara, Subha Rastogi and AKS Rawat. Effect of Asparagus racemosus (shatavari) extract on physicochemical and functional properties of milk and its interaction with milk proteins.Journal of Food Science and Technology, 2015, 52(2):1176–1181.

 S. Patel, S. Shende, Sumit Arora, R.R.B. Singh, Subha Rastogi and AKS Rawat. Antioxidant potential of herbs and spices during deep frying of ghee. International Journal of Dairy Technology, 2014, 67:365-372.

 N. Veena, Sumit Arora, S. Kapila, R.R.B. Singh, Antariksh Katara, M.M. Pandey, Subha Rastogi and AKS Rawat. Immunomodulatory and antioxidative potential of milk fortified with Asparagus racemosus (shatavari). Journal of Medicinal Plants Studies, 2014, 2(6):13-19.

 Subha Rastogi, M.M. Pandey and A.K.S. Rawat. Medicinal plants of genus Betula-Traditional uses and a phytochemical-pharmacological review. Journal of Ethnopharmacology, 2015, 159: 62-83.

 A.K. Tyagi, U.K. Shandilya, A. Srivastava, A. Tyagi, M. Kumar, Subha Rastogi, A.K.S. Rawat and R.R.B. Singh. Effect of different plant extracts, fatty acid and oils on conjugated linoleic acid (CLA) production by Butyrivibrio fibrisolvens. Indian Journal of Animal Sciences, 2015, 85(3):282-286.

 Subha Rastogi, M.M. Pandey, and A.K.S. Rawat. Traditional herbs: a remedy for cardiovascular disorders. Phytomedicine, 2016, 23: 1082–1089.

 M.M. Pandey, S. Khatoon, Subha Rastogi, and A.K.S. Rawat. Determination of flavonoids, polyphenols and antioxidant activity of Tephrosia purpurea: a seasonal study. Journal of Integrative Medicine, 2016; 14(6): 447–455.

 Subha Rastogi, M.M. Pandey and A.K.S. Rawat. Spices: Therapeutic Potential in Cardiovascular Health. Current Pharmaceutical Design, 2017; 23(7): 989-998.

 Subha Rastogi, M M Pandey & AKS Rawat. Phytochemical analysis, phenolic content and antioxidant properties of different parts of Terminalia bellerica (Gaertn.) Roxb.- A comparative study. Indian Journal of Traditional Knowledge,2018, 17(2) 370-375.

 P.K. Murthy, V. Kushwaha, Subha Rastogi, M.M. Pandey, K. Saxena, S. Khatoon and A.K.S. Rawat. In vitro and in vivo antifilarial activity of standardized extract of Calotropis procera flowers against Brugia malayi. Current Topics in Medicinal Chemistry, 2019, 19(14): 1252-1262.

 Subha Rastogi*, M.M. Pandey, A.K.S. Rawat, Vikas Kushwaha and P. K. Murthy. In vitro antifilarial activity, antioxidant potential and phenolic constituents of Quisqualis indica L. Indian Journal of Traditional Knowledge, 2019, 18(4): 648-654.

S. Khatoon, S. Irshad, M.M. Pandey, Subha Rastogi and A.K.S. Rawat A validated high performance thin layer chromatography densitometric method for determination of lupeol, beta-sitosterol and rotenone in Tephrosia purpurea: a seasonal studyJournal of Chromatographic Science, 2019, 57(8): 688-696.

 

Dr. Subha Rastogi

Principal Scientist

Patents

Patent: 10 nos.

– “A process for the preparation of cardanolides.” Ranjeet Kumar Chatterjee, Bhola Nath Dhawan, Anil Kumar Dwivedi, Nigar Fatma, D K Kulshreshtha, B N  Mehrotra, Gyanendra Kumar Patnaik, Puvvada Kalpana  Murthy, Raghwendra Pal, Subha Rastogi, N K Sharma, A K Shaw & Satyawan Singh. Patent No. IN 184010   dated 12/8/2000.

“A process for the extraction of a glycoside fraction from the plant Streblus as per mainly containing cardanolide.” Ranjeet Kumar Chatterjee, Bhola Nath Dhawan, Anil Kumar Dwivedi, Nigar Fatma, D K Kulshreshtha, B N Mehrotra, Gynendra Kumar Patnaik, Puvvada Kalpana Murthy, Raghwendra Pal, Subha Rastogi, N K Sharma, A K Shaw & Satyawan Singh. Patent No. IN 184894   dated 5/18/2001.

“A process for the extraction of a formulations mainly containing bacosides.”  Geetika Bhatia, Bhola Nath Dhawan, Ved Prakash Kamboj, D K Kulshreshtha, B N Mehrotra, Raghwendra Pal, Gyanendra Kumar Patnaik, Subha Rastogi, N Savita Srivastava, Chinta Mani Singh, Hemant Kumar Singh, Satyawan Singh & G Shanker. Patent No. IN 185078   dated 6/15/2001

“Fermented herbal health drink from plant Andrographis.” Pushpangadan, Palpu; Mehrotra, Shanta; Rawat, Ajay Kumar Singh; Khatoon, Sayyada; Srivastava, Sharad Kumar; Rastogi, Subha; Chaubay, Manjoosha; Agnihotri, Adarsh Kumar. Patent No.US 6616950 dated 09/09/2003, AU 2002228290 dated 30/09/2005, RU 2304399 dated 20/08/2007, IN 227860 dated 22/01/2009,

“Herbal soft drink.” Palpu, Pushpangadan; Mehrotra, Shanta; Rawat, Ajay Kumar Singh; Khatoon, Sayyada; Ojha, Sanjeev Kumar; Rastogi, Subha; Srivastava, Manjoosha; Seth, Prahlad Kishore; Agarwal, Ashok Kumar; Kakkar, Poonam; Anand, Mohini. Patent No. US 7550163 dated 23/06/2009, IN 233541 dated 30/03/2009, RU 2336891 dated 27.10.2008.

“Curative alcohol-free herbal drink.” Pushpangadan, Palpu; Mehrotra, Shanta; Ojha, Sanjeev Kumar; Khatoon, Sayyada; Rawat, Ajay Kumar Singh; Rastogi, Subha; Srivastava, Manjoosha; Seth, Prahlad Kishore; Kakkar, Poonam; Agarwal, Ashok Kumar; Anand, Mohini. Patent No. RU 2338431 dated 20.11.2008.

“A Synergistic Herbal Composition For Treatment Of Rheumatic And Musculo-Skeletal Disorders (RMSDS).” Raut Ashwini Kumar, Raghavan Govindarajan, Rastogi Subha, Khatoon Sayyada, Rawat Ajay Kumar Singh, Mehrotra Shanta, Pushpangadam Palpu, Sumantran Venil N, Mujumdar Arvind Manohar, Qazi Ghulam Nabi, Bichile Lata S, Handa Rohini, Narsimulu Gumdal, Chopra Arvind, Patwardhan Bhushan. Patent no. EP-2175871B1 dated 31.08.16

“A bioactive fraction from Calotropis species useful for the treatment of filaria.” Tuli, R., Rawat, A.K.S.,  Khatoon, S., Srivastava, S., Rastogi Subha, Pandey, M.M., Saxena, K., Kushwaha, V. and Murthy, P.K. Patent appl. No. 1695DEL2010.

“A phyto-pharmaceutical preparation for the control of acaricide resistant tick infestations in animals.” Srikant Ghosh, A K Singh Rawat, Sharad Srivastava, Subha Rastogi, D Ray, A K Sharma, S S Tiwari, P Chaudhuri and A. Bandyopadhyay. Patent appl. No. 2452/DEL/2010.

“A phyto-pharmaceutical preparation useful for the improvement in memory impairment.” Rawat Ajay Kumar Singh, Khatoon, Sayyada, Srivastava Sharad, Rastogi, Subha,  Pandey, Madan Mohan, Nath Chandishwar, Khanna Vinay Kumar and Agarwal Ashok Kumar. (49NF2013)

Dr. Subha Rastogi

Principal Scientist

Research Scholars

Dr. Subha Rastogi

Principal Scientist

Address

CSIR-National Botanical Research Institute, Rana Pratap Marg, Lucknow -226001

Phone no.: 0522-2297819

Email:  srastogi@nbri.res.in, rastogi_subha@yahoo.co.in