Dr. Indraneel Sanyal

Senior Principal Scientist

Research Interests

The current interest of our lab is to understand the factors necessary for management of abiotic and biotic stress in model plant Arabidopsis thaliana as well as in tomato, chickpea and mustard. We are studying four genes namely metallothionein, glutaredoxin, CAMTA-1, and Cocculus hirsutus protease inhibitor genes for their roles in abiotic and biotic stress management. We are trying to enhance drought tolerance and crop productivity in the plants against biotic and abiotic stresses through transgenic and genome editing approaches.

Dr. Indraneel Sanyal

Senior Principal Scientist

Research Summary

– Overcoming drought stress in chickpea, by the expression of CAMTA transcription factor.

– Expression of chickpea glutaredoxin gene in chickpea, for tolerance to terminal drought.

– Improvement of water stress tolerance in chickpea by genome editing.

– Combating drought and heavy metal stress in chickpea and mustard by the expression of  metallothione in gene.

– Tolerance to chickpea pod borer by the expression of Cocculus hirsutus trypsin inhibitor.

– Increased crop productivity in mustard by genome editing.

Dr. Indraneel Sanyal

Senior Principal Scientist


– Dubey A. K., Kumar N., Kumar Anil, Ansari M. A., Ranjan R., Gautam A., Meenakshi, Sahu N., Pandey V., Behera S. K., Mallick S., Pande V. and Sanyal I. (2019). Over-expression of CarMT gene modulates the physiological performance and antioxidant defense system to provide tolerance against drought stress in Arabidopsis thaliana L. Ecotoxicology and Environmental Safety, 171: 54-65.

– Dubey A.K., Kumar N., Ranjan R., Gautam A., Pandey V., Sanyal I., and Mallick S. (2018). Application of glycine reduces arsenic accumulation and toxicity in Oryza sativa L. by reducing the expression of silicon transporter genes. Ecology and Environmental Safety, 148: 410-417.

– Yadav, R., Mehrotra, M., Singh, A.K., Niranjan, A., Singh, R., Sanyal, I., Lehri, A., Pande, V., and Amla, D.V. (2017). Improvement in Agrobacterium-mediated transformation of chickpea (Cicer arietinum L.) by the inhibition of polyphenolics released during wounding of cotyledonary node explants. Protoplasma, 254: 253-269.

– Singh, R., Yadav, Y., Amla, D.V. and Sanyal, I. (2016). Characterization and functional validation of two scaffold attachment regions (SARs) from Cicer arietinum (L.). Plant Cell Tissue and Organ Culture, 125: 135-148.

– Pandey, P., Misra, P., Choudhary, D., Yadav, R., Goel, R., Bhambhani, S., Sanyal, I., Trivedi, R., and Trivedi, P.K. (2015). AtMYB12 expression in tomato leads to large scale differential modulation in transcriptome and flavonoid content in leaf and fruit tissues. Scientific Reports, 5: 12412.

– Jha, S., Sanyal, I., and Amla, D.V. (2014). Single amino acid substitutions in recombinant plant-derived human α1-proteinase inhibitor confer enhanced stability and functional efficacy. Biochimica et Biophysica Acta (BBA) – General Subjects, 1840: 416–427.

– Mishra, S., Jha, S., Singh, R., Chaudhary, S., Sanyal, I., and Amla, D.V. (2013). Transgenic chickpea expressing a recombinant human α1-proteinase inhibitor (α1-PI) driven by a seed-specific promoter from the common bean Phaseolus vulgaris (L.). Plant Cell, Tissue and Organ Culture, 115: 23-33.

– Koul, B. Yadav R., Sanyal I., Sawant, S. Sharma V., and Amla D.V. (2012). Cis-acting motifs in artificially synthesized expression cassette leads to enhanced transgene expression in tomato (Solanum lycopersicum L.). Plant Physiology and Biochemistry, 61: 131-141.

– Mehrotra, M., Singh, A.K., Sanyal, I., Altosaar, I. and Amla, D.V. (2011). Pyramiding of modified cry1Ab and cry1Ac genes of Bacillus thuringiensis in transgenic chickpea (Cicer arietinum L.) for improved resistance to pod borer insect Helicoverpa armigera. Euphytica, 182: 87–102.

– Agarwal, S., Jha, S., Sanyal, I. and Amla, D.V. (2010). Expression and purification of recombinant human α1-proteinase inhibitor and its single amino acid substituted variants in Escherichia coli for enhanced stability and biological activity. Journal of Biotechnology, 147: 64-72.

Dr. Indraneel Sanyal

Senior Principal Scientist


Dr. Indraneel Sanyal

Senior Principal Scientist

Research Scholars

Mr. Arvind Kumar Dubey

Mr. Anil Kumar

Ms. Meenakshi

Mr. Ankesh Anant Pandey

Mr. Sanoj Kumar

Mr. Varun Kumar

Ms. Swati Lal

Ms. Ankita Yadav

Ms. Priya Shukla

Ms. Uma Gupta

Dr. Indraneel Sanyal

Senior Principal Scientist


Plant Transgenic Laboratory, Molecular Biology and Biotechnology Division

CSIR-National Botanical Research Institute, P.O. Box 436, Rana Pratap Marg, Lucknow-226001

Phone: 0522-2297955 

Email: i.sanyal@nbri.res.in